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abstract::The A23187 induced calcium uptake in ATP depleted cells was determined at pH 6.9 in the presence of trifluoperazine (TFP, 0.30 mM), compound 48/80 (0.89 mg/ml), 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate (TMB-8, 2.13 mM) and verapamil (1.81 mM). Apart from verapamil the drugs all increased the maximum rate of ...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/0143-4160(84)90022-8
更新日期:1984-10-01 00:00:00
abstract::Incubation of human erythrocyte ghosts with an equal volume of 0.2 mM EDTA in isotonic KCl decreased both the activity and Ca2+ sensitivity of the (Ca2+ + Mg2+)-ATPase remaining associated with the membrane. Readdition of the EDTA-extract activated the (Ca2+ + Mg2+)-ATPase activity. The activator activity was trypsin ...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/0143-4160(84)90156-8
更新日期:1984-02-01 00:00:00
abstract::The sensitivity to Ca2+ of the Ca2+-dependent K+ channel can be increased by the artificial electron donor system ascorbate + phenazine-methosulphate in a variety of animal cells. In the human erythrocyte the shift from the 'low' to the 'high-affinity' state seems to depend on the reduction of a membrane component acc...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/0143-4160(83)90024-6
更新日期:1983-12-01 00:00:00
abstract::An enzymatically active Ca2+-stimulated ATPase has been isolated from the sarcolemmal sheets of human smooth muscle (myometrium). Ca2+-ATPase activity was quantitated in an assay medium which simulated the characteristic free ionic concentrations of the cytosol. New computer programs for calculating the composition of...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/0143-4160(83)90001-5
更新日期:1983-10-01 00:00:00
abstract::R24571 a derivative of the antimycotic miconazole, appears to be 5 to 8 times more potent than trifluoperazine in its ability to inhibit the calmodulin-dependent phosphorylation of cardiac sarcoplasmic reticulum vesicles. The cAMP-dependent protein kinase mediated phosphorylation of cardiac sarcoplasmic reticulum was ...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/0143-4160(83)90039-8
更新日期:1983-04-01 00:00:00
abstract::We have found that the changes in calcium metabolism in rabbit neutrophils produced by the chemotactic synthetic peptide f-Met-Leu-Phe are not sensitive to the calcium chelator EGTA. The present results demonstrate unambiguously that the previously described chemotactic factor induced changes in 45Ca fluxes in rabbit ...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/0143-4160(83)90049-0
更新日期:1983-02-01 00:00:00
abstract::When the concentrations of either calcium or of magnesium in the culture medium were increased from the normal 0.6 and 1.0 mM to 1.8 and 2.5 mM respectively mitotic activity of rat thymic lymphocytes increased. Very high (10(-4)M) ouabain concentrations abolished these mitogenic actions whilst lower (10(-7) and 10(-11...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/0143-4160(83)90044-1
更新日期:1983-02-01 00:00:00
abstract::The rat parotid salivary gland shows marked alterations in phospholipid metabolism when stimulated by certain agonists. These agonists are those which cause cellular Ca mobilization by activation of muscarinic, alpha-adrenergic or peptidergic (substance P) receptors. The phospholipid changes apparently reflect the act...
journal_title:Cell calcium
pub_type: 杂志文章,评审
doi:10.1016/0143-4160(82)90024-0
更新日期:1982-10-01 00:00:00
abstract::The tissue/medium distribution of the nonmetabolized glucose analog [14C]-3-O-methyl-D-glucose was measured in pigeon erythrocytes and related to changes in 45Ca uptake and efflux, total calcium content and ATP levels. Sugar transport was not affected by changes in external Ca2+. However, both sugar and 45Ca influx we...
journal_title:Cell calcium
pub_type: 杂志文章
doi:10.1016/0143-4160(82)90004-5
更新日期:1982-08-01 00:00:00